ERK1/2-Nanog signaling pathway enhances CD44(+) cancer stem-like cell phenotypes and epithelial-to-mesenchymal transition in head and neck squamous cell carcinomas

Head and neck squamous cell carcinomas (HNSCCs) harbor a subset of cells that are CD44(+) and present with malignancy and radiotherapy resistance. As a key regulator of self-renewal, Nanog expression not only determines cell fate in pluripotent cells but also mediates tumorigenesis in cancer cells;...

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Detalles Bibliográficos
Autores principales: Huang, Chuang, Yoon, Changhwan, Zhou, Xiao-Hong, Zhou, Ying-Chun, Zhou, Wen-Wen, Liu, Hong, Yang, Xin, Lu, Jun, Lee, Sei Young, Huang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181750/
https://www.ncbi.nlm.nih.gov/pubmed/32327629
http://dx.doi.org/10.1038/s41419-020-2448-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181750/
https://www.ncbi.nlm.nih.gov/pubmed/32327629
http://dx.doi.org/10.1038/s41419-020-2448-6

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