Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration

Gas1 and Boc/Cdon act as co-receptors in the vertebrate Hedgehog signalling pathway, but the nature of their interaction with the primary Ptch1/2 receptors remains unclear. Here we demonstrate, using primordial germ cell migration in mouse as a developmental model, that specific hetero-complexes of...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Yeonjoo, Lee, Jiyoung, Seppala, Maisa, Cobourne, Martyn T., Kim, Soo-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181751/
https://www.ncbi.nlm.nih.gov/pubmed/32332736
http://dx.doi.org/10.1038/s41467-020-15897-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181751/
https://www.ncbi.nlm.nih.gov/pubmed/32332736
http://dx.doi.org/10.1038/s41467-020-15897-3

Ejemplares similares