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Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming

Fibroblasts are an essential cell population for human skin architecture and function. While fibroblast heterogeneity is well established, this phenomenon has not been analyzed systematically yet. We have used single-cell RNA sequencing to analyze the transcriptomes of more than 5,000 fibroblasts fr...

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Detalles Bibliográficos
Autores principales: Solé-Boldo, Llorenç, Raddatz, Günter, Schütz, Sabrina, Mallm, Jan-Philipp, Rippe, Karsten, Lonsdorf, Anke S., Rodríguez-Paredes, Manuel, Lyko, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181753/
https://www.ncbi.nlm.nih.gov/pubmed/32327715
http://dx.doi.org/10.1038/s42003-020-0922-4