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A necroptotic-independent function of MLKL in regulating endothelial cell adhesion molecule expression

Mixed-lineage kinase domain-like protein (MLKL) is known as the terminal executor of necroptosis. However, its function outside of necroptosis is still not clear. Herein, we demonstrate that MLKL promotes vascular inflammation by regulating the expression of adhesion molecules ICAM1, VCAM1, and E-se...

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Detalles Bibliográficos
Autores principales: Dai, Jialin, Zhang, Chonghe, Guo, Lin, He, Hao, Jiang, Kai, Huang, Yingying, Zhang, Xixi, Zhang, Haibing, Wei, Wu, Zhang, Yaoyang, Lu, Lihua, Hu, Junhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181788/
https://www.ncbi.nlm.nih.gov/pubmed/32332696
http://dx.doi.org/10.1038/s41419-020-2483-3