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Functional arrays of human pluripotent stem cell-derived cardiac microtissues

To accelerate the cardiac drug discovery pipeline, we set out to develop a platform that would be capable of quantifying tissue-level functions such as contractile force and be amenable to standard multiwell-plate manipulations. We report a 96-well-based array of 3D human pluripotent stem cell (hPSC...

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Detalles Bibliográficos
Autores principales: Thavandiran, Nimalan, Hale, Christopher, Blit, Patrick, Sandberg, Mark L., McElvain, Michele E., Gagliardi, Mark, Sun, Bo, Witty, Alec, Graham, George, Do, Van T.H., Bakooshli, Mohsen Afshar, Le, Hon, Ostblom, Joel, McEwen, Samuel, Chau, Erik, Prowse, Andrew, Fernandes, Ian, Norman, Andreea, Gilbert, Penney M., Keller, Gordon, Tagari, Philip, Xu, Han, Radisic, Milica, Zandstra, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181791/
https://www.ncbi.nlm.nih.gov/pubmed/32332814
http://dx.doi.org/10.1038/s41598-020-62955-3