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Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer

Genetics and immunologic dynamics pushing the evolution of colorectal cancer (CRC) from the primary tumor to the metastases are largely unknown; cancer heterogeneity makes challenging both therapy and mechanistic studies. We selected patients developing CRC with lung-limited metastatic disease as on...

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Detalles Bibliográficos
Autores principales: Ottaiano, Alessandro, Circelli, Luisa, Lombardi, Angela, Scala, Stefania, Martucci, Nicola, Galon, Jerome, Buonanno, Manuela, Scognamiglio, Giosuè, Botti, Gerardo, Hermitte, Fabienne, Savarese, Giovanni, D’Amore, Luigi, Tatangelo, Fabiana, Di Mauro, Annabella, Liguori, Giuseppina, Trotta, Anna Maria, Napolitano, Maria, Capozzi, Monica, Tafuto, Salvatore, Perri, Francesco, La Rocca, Antonello, Caraglia, Michele, Nasti, Guglielmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181838/
https://www.ncbi.nlm.nih.gov/pubmed/32332709
http://dx.doi.org/10.1038/s41419-020-2480-6