Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation

Plexins are receptors for semaphorins that transduce signals for regulating neuronal development and other processes. Plexins are single-pass transmembrane proteins with multiple domains in both the extracellular and intracellular regions. Semaphorin activates plexin by binding to its extracellular...

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Detalles Bibliográficos
Autores principales: Kuo, Yi-Chun, Chen, Hua, Shang, Guijun, Uchikawa, Emiko, Tian, Hui, Bai, Xiao-Chen, Zhang, Xuewu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181871/
https://www.ncbi.nlm.nih.gov/pubmed/32327662
http://dx.doi.org/10.1038/s41467-020-15862-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181871/
https://www.ncbi.nlm.nih.gov/pubmed/32327662
http://dx.doi.org/10.1038/s41467-020-15862-0

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