TALEN mediated gene editing in a mouse model of Fanconi anemia

The promising ability to genetically modify hematopoietic stem and progenitor cells by precise gene editing remains challenging due to their sensitivity to in vitro manipulations and poor efficiencies of homologous recombination. This study represents the first evidence of implementing a gene editin...

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Detalles Bibliográficos
Autores principales: Pino-Barrio, Maria José, Giménez, Yari, Villanueva, Mariela, Hildenbeutel, Marcus, Sánchez-Dominguez, Rebeca, Rodríguez-Perales, Sandra, Pujol, Roser, Surrallés, Jordi, Río, Paula, Cathomen, Toni, Mussolino, Claudio, Bueren, Juan Antonio, Navarro, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181878/
https://www.ncbi.nlm.nih.gov/pubmed/32332829
http://dx.doi.org/10.1038/s41598-020-63971-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181878/
https://www.ncbi.nlm.nih.gov/pubmed/32332829
http://dx.doi.org/10.1038/s41598-020-63971-z

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