Heterogeneous cancer associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner

Heterogeneous prostatic carcinoma associated fibroblasts (CAF) contribute to tumor progression and resistance to androgen signaling deprivation therapy (ADT). CAF subjected to extended passaging, compared to low passage CAF, were found to lose tumor expansion potential and heterogeneity. Cell surfac...

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Detalles Bibliográficos
Autores principales: Kato, Manabu, Placencio-Hickok, Veronica R., Madhav, Anisha, Haldar, Subhash, Tripathi, Manisha, Billet, Sandrine, Mishra, Rajeev, Smith, Bethany, Rohena-Rivera, Krizia, Agarwal, Priyanka, Duong, Frank, Angara, Bryan, Hickok, David, Liu, Zhenqiu, Bhowmick, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182071/
https://www.ncbi.nlm.nih.gov/pubmed/30177832
http://dx.doi.org/10.1038/s41388-018-0461-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182071/
https://www.ncbi.nlm.nih.gov/pubmed/30177832
http://dx.doi.org/10.1038/s41388-018-0461-3

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