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Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents

Variants in genes encoding synaptic adhesion proteins of the neuroligin family, most notably neuroligin-4, are a significant cause of autism spectrum disorders in humans. Although human neuroligin-4 is encoded by two genes, NLGN4X and NLGN4Y, that are localized on the X-specific and male-specific re...

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Detalles Bibliográficos
Autores principales: Maxeiner, Stephan, Benseler, Fritz, Krasteva-Christ, Gabriela, Brose, Nils, Südhof, Thomas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182215/
https://www.ncbi.nlm.nih.gov/pubmed/32011705
http://dx.doi.org/10.1093/molbev/msaa014