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Quantitative analysis of the BRAF V595E mutation in plasma cell-free DNA from dogs with urothelial carcinoma

Circulating tumor DNA (ctDNA), which carries tumor-specific mutations, is an emerging candidate biomarker for malignancies and for monitoring disease status in various human tumors. Recently, BRAF V595E mutation has been reported in 80% of dogs with urothelial carcinoma. This study investigates the...

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Detalles Bibliográficos
Autores principales: Tagawa, Michihito, Tambo, Naomi, Maezawa, Masaki, Tomihari, Mizuki, Watanabe, Ken-ichi, Inokuma, Hisashi, Miyahara, Kazuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182225/
https://www.ncbi.nlm.nih.gov/pubmed/32330187
http://dx.doi.org/10.1371/journal.pone.0232365