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O-linked β-N-acetylglucosamine transferase plays an essential role in heart development through regulating angiopoietin-1

O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) is the only enzyme catalyzing O-GlcNAcylation. Although it has been shown that OGT plays an essential role in maintaining postnatal heart function, its role in heart development remains unknown. Here we showed that loss of OGT in early fetal ca...

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Detalles Bibliográficos
Autores principales: Mu, Yongxin, Yu, Houzhi, Wu, Tongbin, Zhang, Jianlin, Evans, Sylvia M., Chen, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182263/
https://www.ncbi.nlm.nih.gov/pubmed/32251422
http://dx.doi.org/10.1371/journal.pgen.1008730