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DOT: Gene-set analysis by combining decorrelated association statistics

Historically, the majority of statistical association methods have been designed assuming availability of SNP-level information. However, modern genetic and sequencing data present new challenges to access and sharing of genotype-phenotype datasets, including cost of management, difficulties in cons...

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Detalles Bibliográficos
Autores principales: Vsevolozhskaya, Olga A., Shi, Min, Hu, Fengjiao, Zaykin, Dmitri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182280/
https://www.ncbi.nlm.nih.gov/pubmed/32287273
http://dx.doi.org/10.1371/journal.pcbi.1007819