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STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism
The MST-LATS kinase cascade is central to the Hippo pathway that controls tissue homeostasis, development, and organ size. The PP2A complex STRIPAK(SLMAP) blocks MST1/2 activation. The GCKIII family kinases associate with STRIPAK, but the functions of these phosphatase-associated kinases remain elus...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182433/ https://www.ncbi.nlm.nih.gov/pubmed/32292165 http://dx.doi.org/10.7554/eLife.54863 |