Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain

Retromer, including Vps35, Vps26, and Vps29, is a protein complex responsible for recycling proteins within the endolysosomal pathway. Although implicated in both Parkinson’s and Alzheimer’s disease, our understanding of retromer function in the adult brain remains limited, in part because Vps35 and...

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Detalles Bibliográficos
Autores principales: Ye, Hui, Ojelade, Shamsideen A, Li-Kroeger, David, Zuo, Zhongyuan, Wang, Liping, Li, Yarong, Gu, Jessica YJ, Tepass, Ulrich, Rodal, Avital Adah, Bellen, Hugo J, Shulman, Joshua M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182434/
https://www.ncbi.nlm.nih.gov/pubmed/32286230
http://dx.doi.org/10.7554/eLife.51977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182434/
https://www.ncbi.nlm.nih.gov/pubmed/32286230
http://dx.doi.org/10.7554/eLife.51977

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