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Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain
Retromer, including Vps35, Vps26, and Vps29, is a protein complex responsible for recycling proteins within the endolysosomal pathway. Although implicated in both Parkinson’s and Alzheimer’s disease, our understanding of retromer function in the adult brain remains limited, in part because Vps35 and...
Autores principales: | Ye, Hui, Ojelade, Shamsideen A, Li-Kroeger, David, Zuo, Zhongyuan, Wang, Liping, Li, Yarong, Gu, Jessica YJ, Tepass, Ulrich, Rodal, Avital Adah, Bellen, Hugo J, Shulman, Joshua M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182434/ https://www.ncbi.nlm.nih.gov/pubmed/32286230 http://dx.doi.org/10.7554/eLife.51977 |
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