Defects in mTORC1 Network and mTORC1-STAT3 Pathway Crosstalk Contributes to Non-inflammatory Hepatocellular Carcinoma

BACKGROUND AND AIMS: Mammalian target of rapamycin complex 1 (mTORC1) is frequently hyperactivated in hepatocellular carcinoma (HCC). Cases of HCC without inflammation and cirrhosis are not rarely seen in clinics. However, the molecular basis of non-inflammatory HCC remains unclear. METHODS: Spontan...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ting, Zhang, Guohong, Wang, Linlin, Li, Susu, Xu, Xiaoping, Gao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182440/
https://www.ncbi.nlm.nih.gov/pubmed/32363190
http://dx.doi.org/10.3389/fcell.2020.00225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182440/
https://www.ncbi.nlm.nih.gov/pubmed/32363190
http://dx.doi.org/10.3389/fcell.2020.00225

Ejemplares similares