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Transcribed B lymphocyte genes and multiple sclerosis risk genes are underrepresented in Epstein–Barr Virus hypomethylated regions

Epstein–Barr Virus (EBV) infection appears to be necessary for the development of Multiple Sclerosis (MS), although the specific mechanisms are unknown. More than 200 single-nucleotide polymorphisms (SNPs) are known to be associated with the risk of developing MS. About a quarter of these are also h...

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Detalles Bibliográficos
Autores principales: Ong, Lawrence T. C., Parnell, Grant P., Afrasiabi, Ali, Stewart, Graeme J., Swaminathan, Sanjay, Booth, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182534/
https://www.ncbi.nlm.nih.gov/pubmed/31619767
http://dx.doi.org/10.1038/s41435-019-0089-5