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Transcribed B lymphocyte genes and multiple sclerosis risk genes are underrepresented in Epstein–Barr Virus hypomethylated regions
Epstein–Barr Virus (EBV) infection appears to be necessary for the development of Multiple Sclerosis (MS), although the specific mechanisms are unknown. More than 200 single-nucleotide polymorphisms (SNPs) are known to be associated with the risk of developing MS. About a quarter of these are also h...
Autores principales: | Ong, Lawrence T. C., Parnell, Grant P., Afrasiabi, Ali, Stewart, Graeme J., Swaminathan, Sanjay, Booth, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182534/ https://www.ncbi.nlm.nih.gov/pubmed/31619767 http://dx.doi.org/10.1038/s41435-019-0089-5 |
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