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Tuning of human NK cells by endogenous HLA-C expression

NK cells are primarily responsible for detecting malignant or pathogen-infected cells, and their function is influenced both by stress-associated activating signals and opposing inhibitory signals from receptors that recognize self MHC. The receptors that produce this inhibitory signal shift from th...

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Detalles Bibliográficos
Autores principales: Goodson-Gregg, Frederick J., Krepel, Stacey A., Anderson, Stephen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182622/
https://www.ncbi.nlm.nih.gov/pubmed/32219494
http://dx.doi.org/10.1007/s00251-020-01161-x