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Oral Azacitidine and Cedazuridine Approximate Parenteral Azacitidine Efficacy in Murine Model

BACKGROUND: DNA methyltransferase inhibitors (DNMTis) improve survival for patients with myelodysplastic syndromes (MDS) and those with acute myeloid leukemia (AML) unable to receive standard cytotoxic chemotherapy and are, accordingly, the backbone of standard-of-care treatment for these conditions...

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Detalles Bibliográficos
Autores principales: Ramsey, Haley E., Oganesian, Aram, Gorska, Agnieszka E., Fuller, Londa, Arrate, Maria, Boyd, Kelli, Keer, Harold, Azab, Mohammad, Savona, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182630/
https://www.ncbi.nlm.nih.gov/pubmed/32222953
http://dx.doi.org/10.1007/s11523-020-00709-x