Ultrasound Assisted Exosomal Delivery of Tissue Responsive mRNA for Enhanced Efficacy and Minimized Off-Target Effects

Exosome-mediated nucleic acids delivery has been emerging as a promising strategy for gene therapy. However, the intrinsic off-target effects due to non-specific uptake of exosomes by other tissues remain the big hurdle for clinical application. In this study, we aimed to enhance the efficacy and mi...

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Detalles Bibliográficos
Autores principales: Sun, Wenqi, Xing, Changyang, Zhao, Lianbi, Zhao, Ping, Yang, Guodong, Yuan, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182664/
https://www.ncbi.nlm.nih.gov/pubmed/32334416
http://dx.doi.org/10.1016/j.omtn.2020.03.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182664/
https://www.ncbi.nlm.nih.gov/pubmed/32334416
http://dx.doi.org/10.1016/j.omtn.2020.03.016

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