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Farnesoid X receptor contributes to body weight-independent improvements in glycemic control after Roux-en-Y gastric bypass surgery in diet-induced obese mice

OBJECTIVE: Roux-en-Y gastric bypass surgery (RYGB) can achieve long-term remission of type 2 diabetes. However, the specific molecular mechanism through which this occurs has remained largely elusive. Bile acid signaling through the nuclear hormone receptor farnesoid X receptor (FXR) exerts benefici...

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Detalles Bibliográficos
Autores principales: Li, Kun, Zou, Jianan, Li, Song, Guo, Jing, Shi, Wentao, Wang, Bing, Han, Xiaodong, Zhang, Hongwei, Zhang, Pin, Miao, Zengmin, Li, Yousheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182762/
https://www.ncbi.nlm.nih.gov/pubmed/32305491
http://dx.doi.org/10.1016/j.molmet.2020.100980