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Farnesoid X receptor contributes to body weight-independent improvements in glycemic control after Roux-en-Y gastric bypass surgery in diet-induced obese mice
OBJECTIVE: Roux-en-Y gastric bypass surgery (RYGB) can achieve long-term remission of type 2 diabetes. However, the specific molecular mechanism through which this occurs has remained largely elusive. Bile acid signaling through the nuclear hormone receptor farnesoid X receptor (FXR) exerts benefici...
Autores principales: | Li, Kun, Zou, Jianan, Li, Song, Guo, Jing, Shi, Wentao, Wang, Bing, Han, Xiaodong, Zhang, Hongwei, Zhang, Pin, Miao, Zengmin, Li, Yousheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182762/ https://www.ncbi.nlm.nih.gov/pubmed/32305491 http://dx.doi.org/10.1016/j.molmet.2020.100980 |
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