Alpha-Synuclein Amyloid Aggregation Is Inhibited by Sulfated Aromatic Polymers and Pyridinium Polycation

The effect of a range of synthetic charged polymers on alpha-synuclein aggregation and amyloid formation was tested. Sulfated aromatic polymers, poly(styrene sulfonate) and poly(anethole sulfonate), have been found to suppress the fibril formation. In this case, small soluble complexes, which do not...

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Detalles Bibliográficos
Autores principales: Semenyuk, Pavel, Kurochkina, Lidia, Barinova, Kseniya, Muronetz, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182936/
https://www.ncbi.nlm.nih.gov/pubmed/32121059
http://dx.doi.org/10.3390/polym12030517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182936/
https://www.ncbi.nlm.nih.gov/pubmed/32121059
http://dx.doi.org/10.3390/polym12030517

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