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The role of activated NLRP3 inflammatory body in acute kidney injury in rats caused by sepsis and NLRP3-TXNIP signaling pathway

OBJECTIVE: The model of acute renal injury (AKI) induced by sepsis in rats was established by abdominal resection through surgical suture. The activation mechanism of nod-like receptor with pyrin domain containing 3 (NLRP3) inflammatory corpuscle in AKI induced by sepsis was analyzed. METHODS: Here,...

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Detalles Bibliográficos
Autores principales: Deng, Huanghao, Chen, Fangzhi, Wang, Yinhuai, Jiang, Hongyi, Dong, Zhitao, Yuan, Biao, Zhao, Xiaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182990/
https://www.ncbi.nlm.nih.gov/pubmed/32346332
http://dx.doi.org/10.1016/j.sjbs.2020.03.018