Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation

Receptor-interacting protein kinase 1 (RIPK1) and 3 (RIPK3) are well known for their capacity to drive necroptosis via mixed-lineage kinase-like domain (MLKL). Recently, RIPK1/3 kinase activity has been shown to drive inflammation via activation of MAPK signaling. However, the regulatory mechanisms...

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Detalles Bibliográficos
Autores principales: Muendlein, Hayley I., Sarhan, Joseph, Liu, Beiyun C., Connolly, Wilson M., Schworer, Stephen A., Smirnova, Irina, Tang, Amy Y., Ilyukha, Vladimir, Pietruska, Jodie, Tahmasebi, Soroush, Sonenberg, Nahum, Degterev, Alexei, Poltorak, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183097/
https://www.ncbi.nlm.nih.gov/pubmed/31968247
http://dx.doi.org/10.1016/j.celrep.2019.12.073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183097/
https://www.ncbi.nlm.nih.gov/pubmed/31968247
http://dx.doi.org/10.1016/j.celrep.2019.12.073

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