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Gene drive and resilience through renewal with next generation Cleave and Rescue selfish genetic elements

Gene drive-based strategies for modifying populations face the problem that genes encoding cargo and the drive mechanism are subject to separation, mutational inactivation, and loss of efficacy. Resilience, an ability to respond to these eventualities in ways that restore population modification wit...

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Detalles Bibliográficos
Autores principales: Oberhofer, Georg, Ivy, Tobin, Hay, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183144/
https://www.ncbi.nlm.nih.gov/pubmed/32245808
http://dx.doi.org/10.1073/pnas.1921698117