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Co-inhibition of BCL-XL and MCL-1 with selective BCL-2 family inhibitors enhances cytotoxicity of cervical cancer cell lines

Development of resistance to chemo- and radiotherapy in patients suffering from advanced cervical cancer narrows the therapeutic window for conventional therapies. Previously we reported that a combination of the selective BCL-2 family inhibitors ABT-263 and A-1210477 decreased cell proliferation in...

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Detalles Bibliográficos
Autores principales: Abdul Rahman, Siti Fairus, Muniandy, Kalaivani, Soo, Yong Kit, Tiew, Elvin Yu Huai, Tan, Ke Xin, Bates, Timothy E., Mohana-Kumaran, Nethia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183162/
https://www.ncbi.nlm.nih.gov/pubmed/32346617
http://dx.doi.org/10.1016/j.bbrep.2020.100756