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Computational design of probes to detect bacterial genomes by multivalent binding

Rapid methods for diagnosis of bacterial infections are urgently needed to reduce inappropriate use of antibiotics, which contributes to antimicrobial resistance. In many rapid diagnostic methods, DNA oligonucleotide probes, attached to a surface, bind to specific nucleotide sequences in the DNA of...

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Detalles Bibliográficos
Autores principales: Curk, Tine, Brackley, Chris A., Farrell, James D., Xing, Zhongyang, Joshi, Darshana, Direito, Susana, Bren, Urban, Angioletti-Uberti, Stefano, Dobnikar, Jure, Eiser, Erika, Frenkel, Daan, Allen, Rosalind J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183166/
https://www.ncbi.nlm.nih.gov/pubmed/32241887
http://dx.doi.org/10.1073/pnas.1918274117