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Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1

OBJECTIVE: To elucidate the neuroprotective function of metformin in suppressing propofol-induced apoptosis of HT-22 cells. METHODS: HT-22 cells were treated with 0, 10 or 100 μmol/L propofol, followed by determination of their proliferative ability. Subsequently, changes in proliferation and apopto...

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Detalles Bibliográficos
Autores principales: Ge, Jianyun, Huang, Yulin, Zhang, Yi, Liu, Lin, Gu, Tianyu, Liu, Xu, Yao, Lei, Cai, Mengmeng, Sun, Jiafeng, Song, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183342/
https://www.ncbi.nlm.nih.gov/pubmed/32368014
http://dx.doi.org/10.2147/DDDT.S229520