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Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1
OBJECTIVE: To elucidate the neuroprotective function of metformin in suppressing propofol-induced apoptosis of HT-22 cells. METHODS: HT-22 cells were treated with 0, 10 or 100 μmol/L propofol, followed by determination of their proliferative ability. Subsequently, changes in proliferation and apopto...
Autores principales: | Ge, Jianyun, Huang, Yulin, Zhang, Yi, Liu, Lin, Gu, Tianyu, Liu, Xu, Yao, Lei, Cai, Mengmeng, Sun, Jiafeng, Song, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183342/ https://www.ncbi.nlm.nih.gov/pubmed/32368014 http://dx.doi.org/10.2147/DDDT.S229520 |
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