Dexmedetomidine Preconditioning Protects Rats from Renal Ischemia–Reperfusion Injury Accompanied with Biphasic Changes of Nuclear Factor-Kappa B Signaling

Acute kidney injury (AKI) is one of the most common and troublesome perioperative complications. Dexmedetomidine (DEX) is a potent α2-adrenoceptor (α2-AR) agonist with anti-inflammatory and renoprotective effects. In this study, a rat renal ischemia–reperfusion injury (IRI) model was induced. At 24 ...

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Detalles Bibliográficos
Autores principales: Bao, Naren, Tang, Bing, Wang, Junke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183529/
https://www.ncbi.nlm.nih.gov/pubmed/32377532
http://dx.doi.org/10.1155/2020/3230490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183529/
https://www.ncbi.nlm.nih.gov/pubmed/32377532
http://dx.doi.org/10.1155/2020/3230490

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