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Transport systems, intracellular traffic of intermediates and secretion of β-lactam antibiotics in fungi
Fungal secondary metabolites are synthesized by complex biosynthetic pathways catalized by enzymes located in different subcellular compartments, thus requiring traffic of precursors and intermediates between them. The β-lactam antibiotics penicillin and cephalosporin C serve as an excellent model t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183595/ https://www.ncbi.nlm.nih.gov/pubmed/32351700 http://dx.doi.org/10.1186/s40694-020-00096-y |