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LC–MS-based multivariate statistical analysis for the screening of potential thrombin/factor Xa inhibitors from Radix Salvia Miltiorrhiza

BACKGROUND: The dry root and rhizome of Salvia miltiorrhiza Bunge, or Danshen, is a well-known traditional Chinese medicine with anticoagulant activity. Taking into account that thrombin (THR) and factor Xa (FXa) play crucial roles in the coagulation cascade, it is reasonable and meaningful to scree...

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Detalles Bibliográficos
Autores principales: Yang, Yi-Yao, Wu, Zhao-Yu, Zhang, Hao, Yin, Shi-Jun, Xia, Fang-Bo, Zhang, Qian, Wan, Jian-Bo, Gao, Jian-Li, Yang, Feng-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183602/
https://www.ncbi.nlm.nih.gov/pubmed/32351617
http://dx.doi.org/10.1186/s13020-020-00320-2