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LC–MS-based multivariate statistical analysis for the screening of potential thrombin/factor Xa inhibitors from Radix Salvia Miltiorrhiza
BACKGROUND: The dry root and rhizome of Salvia miltiorrhiza Bunge, or Danshen, is a well-known traditional Chinese medicine with anticoagulant activity. Taking into account that thrombin (THR) and factor Xa (FXa) play crucial roles in the coagulation cascade, it is reasonable and meaningful to scree...
Autores principales: | Yang, Yi-Yao, Wu, Zhao-Yu, Zhang, Hao, Yin, Shi-Jun, Xia, Fang-Bo, Zhang, Qian, Wan, Jian-Bo, Gao, Jian-Li, Yang, Feng-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183602/ https://www.ncbi.nlm.nih.gov/pubmed/32351617 http://dx.doi.org/10.1186/s13020-020-00320-2 |
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