CRISPR/Cas9-deaminase enables robust base editing in Rhodobacter sphaeroides 2.4.1

BACKGROUND: CRISPR/Cas9 systems have been repurposed as canonical genome editing tools in a variety of species, but no application for the model strain Rhodobacter sphaeroides 2.4.1 was unveiled. RESULTS: Here we showed two kinds of programmable base editing systems, cytosine base editors (CBEs) and...

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Detalles Bibliográficos
Autores principales: Luo, Yufeng, Ge, Mei, Wang, Bolun, Sun, Changhong, Wang, Junyi, Dong, Yuyang, Xi, Jianzhong Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183636/
https://www.ncbi.nlm.nih.gov/pubmed/32334589
http://dx.doi.org/10.1186/s12934-020-01345-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183636/
https://www.ncbi.nlm.nih.gov/pubmed/32334589
http://dx.doi.org/10.1186/s12934-020-01345-w

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