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CRISPR/Cas9-deaminase enables robust base editing in Rhodobacter sphaeroides 2.4.1

BACKGROUND: CRISPR/Cas9 systems have been repurposed as canonical genome editing tools in a variety of species, but no application for the model strain Rhodobacter sphaeroides 2.4.1 was unveiled. RESULTS: Here we showed two kinds of programmable base editing systems, cytosine base editors (CBEs) and...

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Detalles Bibliográficos
Autores principales:	Luo, Yufeng, Ge, Mei, Wang, Bolun, Sun, Changhong, Wang, Junyi, Dong, Yuyang, Xi, Jianzhong Jeff
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183636/ https://www.ncbi.nlm.nih.gov/pubmed/32334589 http://dx.doi.org/10.1186/s12934-020-01345-w

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