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Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei
BACKGROUND: Vacuolar H(+)-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles. Beyond its role in pH maintenance, the involvement of V-ATPase in endocytosis is well documented in mammals and plants but is less clear in Trypanoso...
Autores principales: | Xu, Zhi-Shen, Li, Feng-Jun, Hide, Geoff, Lun, Zhao-Rong, Lai, De-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183646/ https://www.ncbi.nlm.nih.gov/pubmed/32334612 http://dx.doi.org/10.1186/s13071-020-04068-4 |
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