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Higher interferon score and normal complement levels may identify a distinct clinical subset in children with systemic lupus erythematosus
BACKGROUND: Systemic lupus erythematosus (SLE) is a complex multi-system disease, characterized by both autoimmune and autoinflammatory clinical and laboratory features. The role of type I interferon (IFN) in SLE has been demonstrated from the 2000s, by gene expression analyses showing significant o...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183668/ https://www.ncbi.nlm.nih.gov/pubmed/32334613 http://dx.doi.org/10.1186/s13075-020-02161-8 |