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Higher interferon score and normal complement levels may identify a distinct clinical subset in children with systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is a complex multi-system disease, characterized by both autoimmune and autoinflammatory clinical and laboratory features. The role of type I interferon (IFN) in SLE has been demonstrated from the 2000s, by gene expression analyses showing significant o...

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Detalles Bibliográficos
Autores principales: Tesser, Alessandra, de Carvalho, Luciana Martins, Sandrin-Garcia, Paula, Pin, Alessia, Pastore, Serena, Taddio, Andrea, Roberti, Luciana Rodrigues, de Paula Queiroz, Rosane Gomes, Ferriani, Virginia Paes Leme, Crovella, Sergio, Tommasini, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183668/
https://www.ncbi.nlm.nih.gov/pubmed/32334613
http://dx.doi.org/10.1186/s13075-020-02161-8