Cargando…

Higher interferon score and normal complement levels may identify a distinct clinical subset in children with systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is a complex multi-system disease, characterized by both autoimmune and autoinflammatory clinical and laboratory features. The role of type I interferon (IFN) in SLE has been demonstrated from the 2000s, by gene expression analyses showing significant o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tesser, Alessandra, de Carvalho, Luciana Martins, Sandrin-Garcia, Paula, Pin, Alessia, Pastore, Serena, Taddio, Andrea, Roberti, Luciana Rodrigues, de Paula Queiroz, Rosane Gomes, Ferriani, Virginia Paes Leme, Crovella, Sergio, Tommasini, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183668/ https://www.ncbi.nlm.nih.gov/pubmed/32334613 http://dx.doi.org/10.1186/s13075-020-02161-8

Ejemplares similares

An Easy and Reliable Strategy for Making Type I Interferon Signature Analysis Comparable among Research Centers
por: Pin, Alessia, et al.
Publicado: (2019)

Systemic Lupus Erythematosus: Old and New Susceptibility Genes versus Clinical Manifestations
por: J, De Azevêdo Silva, et al.
Publicado: (2014)

Biological and Clinical Changes in a Pediatric Series Treated with Off-Label JAK Inhibitors
por: Pin, Alessia, et al.
Publicado: (2020)

Pulmonary arterial hypertension in interferonophaties: a case report and a review of the literature
por: Trombetta, A., et al.
Publicado: (2019)

Chronic recurrent multifocal osteomyelitis: experience from a single pediatric rheumatology center over the past ten years
por: Pastore, Serena, et al.
Publicado: (2014)

A toddler with an unusually severe polyarticular arthritis and a lung involvement: a case report
por: Basile, Pietro, et al.
Publicado: (2022)

Complement and systemic lupus erythematosus
por: Walport, Mark J
Publicado: (2002)

Homocysteine, folate, hs-C-reactive protein, tumor necrosis factor alpha and inflammatory proteins: are these biomarkers related to nutritional status and cardiovascular risk in childhood-onset systemic lupus erythematosus?
por: Salomão, Roberta Garcia, et al.
Publicado: (2018)

Acute respiratory infections, influenza-like illness and JIA: impact on disease activity and response to the influenza vaccine
por: Carvalho, Luciana M, et al.
Publicado: (2012)

Proportions of B-cell subsets are altered in incomplete systemic lupus erythematosus and correlate with interferon score and IgG levels
por: Henning, Svenja, et al.
Publicado: (2020)

Prospective surveillance study of acute respiratory infections, influenza-like illness and seasonal influenza vaccine in a cohort of juvenile idiopathic arthritis patients
por: Carvalho, Luciana M, et al.
Publicado: (2013)

Priming of the cGAS-STING-TBK1 Pathway Enhances LPS-Induced Release of Type I Interferons
por: Tesser, Alessandra, et al.
Publicado: (2021)

Disease activity index is associated with subclinical atherosclerosis in childhood-onset systemic lupus erythematosus
por: Medeiros, Priscila B. S., et al.
Publicado: (2021)

Social phobia in childhood-onset systemic lupus erythematosus
por: Nascimento, Catia, et al.
Publicado: (2014)

Interferon Alpha in Systemic Lupus Erythematosus
por: Niewold, Timothy B., et al.
Publicado: (2010)

Complement as a Biomarker for Systemic Lupus Erythematosus
por: Ayano, Masahiro, et al.
Publicado: (2023)

Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus
por: Katsuyama, Takayuki, et al.
Publicado: (2018)

Genetic profiling of auto-inflammatory disorders in patients with periodic fever: a prospective study
por: De Pieri, Carlo, et al.
Publicado: (2014)

In Vitro Effects of Sulforaphane on Interferon-Driven Inflammation and Exploratory Evaluation in Two Healthy Volunteers
por: Genova, Elena, et al.
Publicado: (2021)

Interferon targeted therapies in systemic lupus erythematosus
por: Misra, Durga Prasanna, et al.
Publicado: (2017)

Complement deficiencies and susceptibility to systemic lupus erythematosus revisited
por: Elkon, KB, et al.
Publicado: (2012)

Coagulation cascade and complement system in systemic lupus erythematosus
por: Liang, Yan, et al.
Publicado: (2017)

Complement deficiency in pediatric-onset systemic lupus erythematosus
por: Afzali, Parisa, et al.
Publicado: (2018)

Genetic and immunologic findings in children with recurrent aphthous stomatitis with systemic inflammation
por: Girardelli, Martina, et al.
Publicado: (2021)

Immunity and Genetics at the Revolving Doors of Diagnostics in Primary Immunodeficiencies
por: Rispoli, Francesco, et al.
Publicado: (2021)

Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus Blood
por: Bennett, Lynda, et al.
Publicado: (2003)

Systemic lupus erythematosus and the type I interferon system
por: Rönnblom, Lars, et al.
Publicado: (2003)

Diminished Expression of Complement Regulatory Proteins on Peripheral Blood Cells from Systemic Lupus Erythematosus Patients
por: Alegretti, Ana Paula, et al.
Publicado: (2012)

Full characterization of the three pathways of the complement system in patients with systemic lupus erythematosus
por: García-González, María, et al.
Publicado: (2023)

Monocyte subsets involved in the development of systemic lupus erythematosus and rheumatoid arthritis
por: Hirose, Sachiko, et al.
Publicado: (2019)

5-aminoimidazole-4-carboxamide ribonucleotide-transformylase and inosine-triphosphate-pyrophosphatase genes variants predict remission rate during methotrexate therapy in patients with juvenile idiopathic arthritis
por: Pastore, Serena, et al.
Publicado: (2014)

Megamonas funiformis, Plasma Zonulin, and Sodium Intake Affect C3 Complement Levels in Inactive Systemic Lupus Erythematosus
por: Balmant, Bianca Depieri, et al.
Publicado: (2023)

Can Cell Bound Complement Activation Products Predict Inherited Complement Deficiency in Systemic Lupus Erythematosus?
por: Raj, Naveen, et al.
Publicado: (2016)

Coexistence of chronic cutaneous lupus erythematosus and frontal fibrosing alopecia
por: do Nascimento, Luciana Lima, et al.
Publicado: (2018)

The Role of Apoptosis Proteins and Complement Components in the Etiopathogenesis of Systemic Lupus Erythematosus
por: Liphaus, Bernadete L., et al.
Publicado: (2010)

Systemic Lupus Erythematosus and Deficiencies of Early Components of the Complement Classical Pathway
por: Macedo, Ana Catarina Lunz, et al.
Publicado: (2016)

Complement levels and risk of organ involvement in patients with systemic lupus erythematosus
por: Gandino, Ignacio Javier, et al.
Publicado: (2017)

HDL Cholesterol Efflux and the Complement System Are Linked in Systemic Lupus Erythematosus
por: García-González, María, et al.
Publicado: (2023)

Interferon Regulatory Factor 5 in the Pathogenesis of Systemic Lupus Erythematosus
por: Cham, Candace M., et al.
Publicado: (2012)

Vasculitis, Autoimmunity, and Cytokines: How the Immune System Can Harm the Brain
por: Tesser, Alessandra, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rp1u7hps916k63pbrvpsr3t1d4