Silencing of microRNA-135b inhibits invasion, migration, and stemness of CD24(+)CD44(+) pancreatic cancer stem cells through JADE-1-dependent AKT/mTOR pathway

BACKGROUND: Recent studies have emphasized determining the ability of microRNAs (miRNAs) as crucial regulators in the occurrence and development of pancreatic cancer (PC), which continues to be one of the deadliest malignancies with few effective therapies. The study aimed to investigate the functio...

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Detalles Bibliográficos
Autores principales: Zhou, Jingyang, Wang, Haihong, Che, Jinhui, Xu, Lu, Yang, Weizhong, Li, Yunjiu, Zhou, Wuyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183669/
https://www.ncbi.nlm.nih.gov/pubmed/32351328
http://dx.doi.org/10.1186/s12935-020-01210-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183669/
https://www.ncbi.nlm.nih.gov/pubmed/32351328
http://dx.doi.org/10.1186/s12935-020-01210-1

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