Synergistic activation of NF-κB by TNFAIP3 (A20) reduction and UBE2L3 (UBCH7) augment that synergistically elevate lupus risk

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune inflammatory rheumatic disease. SLE susceptibility is affected by multiple genetic elements, environmental factors, and their interactions. We aimed in this study to statistically and functionally characterize a gene-gene interaction (e...

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Detalles Bibliográficos
Autores principales: Kim, Taehyeung, Bae, Sang-Cheol, Kang, Changwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183688/
https://www.ncbi.nlm.nih.gov/pubmed/32334614
http://dx.doi.org/10.1186/s13075-020-02181-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183688/
https://www.ncbi.nlm.nih.gov/pubmed/32334614
http://dx.doi.org/10.1186/s13075-020-02181-4

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