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Acute mechanical stress in primary porcine RPE cells induces angiogenic factor expression and in vitro angiogenesis

BACKGROUND: Choroidal neovascularization (CNV) is a major cause of blindness in patients with age-related macular degeneration. CNV is characterized by new blood vessel growth and subretinal fluid accumulation, which results in mechanical pressure on retinal pigment epithelial (RPE) cells. The overe...

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Detalles Bibliográficos
Autores principales: Farjood, Farhad, Ahmadpour, Amir, Ostvar, Sassan, Vargis, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183714/
https://www.ncbi.nlm.nih.gov/pubmed/32355505
http://dx.doi.org/10.1186/s13036-020-00235-4