Viral protein X unlocks the nuclear pore complex through a human Nup153-dependent pathway to promote nuclear translocation of the lentiviral genome

Simian immunodeficiency virus (SIV) and human immunodeficiency virus 2 (HIV-2) display unique ability to infect nondividing target cells. Viral protein X (Vpx) of HIV-2/SIV is known to be involved in the nuclear import of viral genome in nondividing cells, but the mechanism remains poorly understood...

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Detalles Bibliográficos
Autores principales: Singh, Satya Prakash, Raja, Sebastian, Mahalingam, Sundarasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183765/
https://www.ncbi.nlm.nih.gov/pubmed/31913756
http://dx.doi.org/10.1091/mbc.E19-08-0438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183765/
https://www.ncbi.nlm.nih.gov/pubmed/31913756
http://dx.doi.org/10.1091/mbc.E19-08-0438

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