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PTEN-induced kinase 1-induced dynamin-related protein 1 Ser637 phosphorylation reduces mitochondrial fission and protects against intestinal ischemia reperfusion injury

BACKGROUND: Intestinal ischemia reperfusion (I/R) occurs in various diseases, such as trauma and intestinal transplantation. Excessive reactive oxygen species (ROS) accumulation and subsequent apoptotic cell death in intestinal epithelia are important causes of I/R injury. PTEN-induced putative kina...

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Detalles Bibliográficos
Autores principales: Qasim, Wasim, Li, Yang, Sun, Rui-Min, Feng, Dong-Cheng, Wang, Zhan-Yu, Liu, De-Shun, Yao, Ji-Hong, Tian, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183859/
https://www.ncbi.nlm.nih.gov/pubmed/32351292
http://dx.doi.org/10.3748/wjg.v26.i15.1758