The lysine methyltransferase SMYD2 is required for normal lymphocyte development and survival of hematopoietic leukemias.

The 5 membered SET and MYND Domain-containing lysine methyltransferase (SMYD) family plays pivotal roles in development and proliferation. Initially characterized within the cardiovascular system, one such member, SMYD2, has been implicated as an oncogene in leukemias deriving from flawed hematopoie...

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Detalles Bibliográficos
Autores principales: Brown, Mark A., Edwards, Melissa A., Alshiraihi, Ilham, Geng, Huimin, Dekker, Joseph D., Tucker, Haley O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183909/
https://www.ncbi.nlm.nih.gov/pubmed/32115575
http://dx.doi.org/10.1038/s41435-020-0094-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183909/
https://www.ncbi.nlm.nih.gov/pubmed/32115575
http://dx.doi.org/10.1038/s41435-020-0094-8

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