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Oncogenic ALK(F1174L) drives tumorigenesis in cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer characterized by increased mortality. Here, we show for the first time that anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase of the insulin receptor superfamily, plays a pivotal role in the pathogenesis of cSC...

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Detalles Bibliográficos
Autores principales: Gualandi, Marco, Iorio, Maria, Engeler, Olivia, Serra-Roma, André, Gasparre, Giuseppe, Schulte, Johannes H, Hohl, Daniel, Shakhova, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184028/
https://www.ncbi.nlm.nih.gov/pubmed/32312912
http://dx.doi.org/10.26508/lsa.201900601