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Microtubule-dependent and independent roles of spastin in lipid droplet dispersion and biogenesis

Lipid droplets (LDs) are metabolic organelles that store neutral lipids and dynamically respond to changes in energy availability by accumulating or mobilizing triacylglycerols (TAGs). How the plastic behavior of LDs is regulated is poorly understood. Hereditary spastic paraplegia is a central motor...

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Detalles Bibliográficos
Autores principales: Tadepalle, Nimesha, Robers, Lennart, Veronese, Matteo, Zentis, Peter, Babatz, Felix, Brodesser, Susanne, Gruszczyk, Anja V, Schauss, Astrid, Höning, Stefan, Rugarli, Elena I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184029/
https://www.ncbi.nlm.nih.gov/pubmed/32321733
http://dx.doi.org/10.26508/lsa.202000715