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NfL and pNfH are increased in Friedreich’s ataxia

OBJECTIVE: To assess neurofilaments as neurodegenerative biomarkers in serum of patients with Friedreich’s ataxia. METHODS: Single molecule array measurements of neurofilament light (NfL) and heavy chain (pNfH) in 99 patients with genetically confirmed Friedreich’s ataxia. Correlation of NfL/pNfH se...

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Detalles Bibliográficos
Autores principales: Hayer, Stefanie Nicole, Liepelt, Inga, Barro, Christian, Wilke, Carlo, Kuhle, Jens, Martus, Peter, Schöls, Ludger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184046/
https://www.ncbi.nlm.nih.gov/pubmed/32002649
http://dx.doi.org/10.1007/s00415-020-09722-6